rdf:type |
|
lifeskim:mentions |
umls-concept:C0020684,
umls-concept:C0034320,
umls-concept:C0035549,
umls-concept:C0205314,
umls-concept:C0243071,
umls-concept:C0243125,
umls-concept:C0439596,
umls-concept:C0679622,
umls-concept:C0699900,
umls-concept:C0718263,
umls-concept:C1550548,
umls-concept:C1555714,
umls-concept:C1705654,
umls-concept:C2700116
|
pubmed:issue |
10
|
pubmed:dateCreated |
2006-3-3
|
pubmed:abstractText |
Cyclic 8-bromo-inosine-5'-diphosphate ribose (8-Br-N1-cIDPR) was cleanly degraded at acidic pH by N9 ribosyl scission and subsequent pyrophosphate cleavage to give 8-bromo-N1-ribosyl hypoxanthine 5'-monophosphate (8-Br-N1-IMP), a novel class of mononucleotide, as the sole product.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
1359-7345
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
14
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1127-9
|
pubmed:dateRevised |
2007-8-13
|
pubmed:meshHeading |
|
pubmed:year |
2006
|
pubmed:articleTitle |
Unusual entry to the novel 8-halo-N1-ribosyl hypoxanthine system by degradation of a cyclic adenosine-5'-diphosphate ribose analogue.
|
pubmed:affiliation |
Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath, UK BA2 7AY.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|