Source:http://linkedlifedata.com/resource/umls/id/C0020684
CSP: 6-oxopurine, the base in inosine and its derivatives.,MSH: A purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway.,NCI: A purine-based organic compound in human muscle tissues, Hypoxanthine is formed during purine catabolism as a product of xanthine oxidase action on xanthine, and occasionally is found as a constituent of nucleic acids. The potent anti-inflammatory and cytoprotective effects of purines may be mediated by cell surface adenosine receptors. Hypoxanthine protects against oxidant-induced cell injury by inhibiting activation of nuclear poly(ADP-ribose) polymerase (PARP). (NCI04)