Source:http://linkedlifedata.com/resource/pubmed/id/16482817
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2006-2-17
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pubmed:abstractText |
This study compares the levels of specific antibodies IgM and IgA for Chagas in samples of blood from newborns. Three groups of cord blood samples have been analysed: a group of 42 samples from newborns, displaying positive parasitemia, of seropositive mothers (M+B+), 68 samples from newborns with negative parasitemia whose mothers were seropositive (M+B-) and a group of 45 control newborns coming from mothers with negative serology for Chagas. From the 42 M+B+ samples with congenital Chagas disease, 81 and 82.9% displayed detectable levels of IgM and IgA antibodies, respectively In the M+B- group, 70.6 and 33.8% presented antibodies of IgM and IgA classes, respectively, whereas in the control group M-B-, we detected 6% and 11.1% of IgM and IgA antibodies, respectively. The calculated sensitivity of detection of congenital cases using IgM or IgA antibodies was of 82.9% and 80.9% respectively, whereas the specificity of detection was of 29.4% for IgM antibodies and of 66.1% for IgA antibodies.
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pubmed:language |
spa
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0037-8682
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38 Suppl 2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
62-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16482817-Animals,
pubmed-meshheading:16482817-Case-Control Studies,
pubmed-meshheading:16482817-Chagas Disease,
pubmed-meshheading:16482817-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16482817-Humans,
pubmed-meshheading:16482817-Immunoglobulin A,
pubmed-meshheading:16482817-Immunoglobulin M,
pubmed-meshheading:16482817-Infant, Newborn,
pubmed-meshheading:16482817-Sensitivity and Specificity,
pubmed-meshheading:16482817-Trypanosoma cruzi
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pubmed:year |
2005
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pubmed:articleTitle |
[Serum levels for IgM and IgA antibodies to anti-trypanosoma cruzi in samples of blood from newborns from mothers with positive serology for Chagas disease].
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pubmed:affiliation |
CUMETROP/LABIMED, Facultad de Medicina, Universidad Mayor de San Simón (UMSS), Cochabamba, Bolivia. patriciarohe@hotmail.com
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pubmed:publicationType |
Journal Article,
English Abstract
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