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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2005-6-15
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pubmed:abstractText |
An atherosclerotic abdominal aortic aneurysms (AAAA) differ from inflammatory abdominal aortic aneurysms (IAAA), which are characterized by a non specific inflammatory reaction leading to considerable aneurysmal wall thickness from the media to adventitia and retroperitoneal fibrosis in the surrounding tissue. Platelet-derived growth factor (PDGF) and its receptor have been localized to specific cell types within atherosclerotic plaques. Human connective tissue growth factor (CTGF) is a cysteine rich polypeptide that has similar structures to PDGF and has been implicated in connective tissue formation. PDGF and CTGF may play a role in the development of aneurysmal walls in both AAAA and IAAA.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0021-9509
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
271-8
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:15956925-Adult,
pubmed-meshheading:15956925-Aged,
pubmed-meshheading:15956925-Aortic Aneurysm, Abdominal,
pubmed-meshheading:15956925-Connective Tissue Growth Factor,
pubmed-meshheading:15956925-Female,
pubmed-meshheading:15956925-Gene Expression,
pubmed-meshheading:15956925-Humans,
pubmed-meshheading:15956925-Immediate-Early Proteins,
pubmed-meshheading:15956925-Immunohistochemistry,
pubmed-meshheading:15956925-In Situ Hybridization,
pubmed-meshheading:15956925-Insulin-Like Growth Factor Binding Proteins,
pubmed-meshheading:15956925-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:15956925-Male,
pubmed-meshheading:15956925-Muscle, Smooth, Vascular,
pubmed-meshheading:15956925-Platelet-Derived Growth Factor,
pubmed-meshheading:15956925-Prognosis,
pubmed-meshheading:15956925-RNA, Messenger
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pubmed:year |
2005
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pubmed:articleTitle |
The expression of platelet-derived growth factor and connective tissue growth factor in different types of abdominal aortic aneurysms.
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pubmed:affiliation |
Division of Cardiovascular Surgery, Himeji Central Hospital, Himeji, Hyogo, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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