Linked Life Data

15928891

Source:http://linkedlifedata.com/resource/pubmed/id/15928891

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2005-6-1
pubmed:abstractText
Aseptic loosening is the major problem associated with joint arthroplasty, but little is known about the precise mechanism of osteolysis. To elucidate this mechanism we analyzed polyethylene particles retrieved from granulation tissue around the stem of loosened hip arthroplasties. Granulation tissue was obtained from 35 patients at revision surgery for a loosened hip and digested with papain, followed by ultracentrifugation. The isolated particles were identified with ultra-high molecular weight polyethylene particles by Fourier transform infrared spectroscopy. The morphology and number of particles were analyzed by scanning electron microscopy. Most of the particles were granular, with 87.9% being less than 1 microm in equivalent circle diameter (mean 0.83 +/- 0.45 microm). The mean number of particles per gram of tissue was 1.48 x 10(9) (range 7.59 x 10(7) to 1.15 x 10(10)). We compared these data to the radiological appearance and found that focal-type osteolysis contained more particles than the linear type. The amount of submicron-sized particles is related to the development of osteolysis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0949-2658
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
284-90
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Analysis of polyethylene particles isolated from periprosthetic tissue of loosened hip arthroplasty and comparison with radiographic appearance.
pubmed:affiliation
Department of Orthopedic Surgery, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
pubmed:publicationType
Journal Article, Comparative Study