rdf:type |
|
lifeskim:mentions |
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0086418,
umls-concept:C0205263,
umls-concept:C0262950,
umls-concept:C0302313,
umls-concept:C0376358,
umls-concept:C0387583,
umls-concept:C1280500,
umls-concept:C1565860,
umls-concept:C1705323
|
pubmed:issue |
1A
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pubmed:dateCreated |
2005-4-8
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pubmed:abstractText |
The mechanism of bone formation by osteoblastic prostate cancer metastases is not well defined. Using knockout mice, it has been demonstrated that prostaglandins produced by COX-2 are critical for fracture repair. Therefore, our aim was to determine if COX-2 plays a role in the bone formation in osteoblastic prostate cancer metastases in bone.
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pubmed:grant |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/4-(5-(4-chlorophenyl)-3-(trifluorome...,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2 Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PTGS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandin-Endoperoxide Synthases,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
25
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
107-15
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15816526-Animals,
pubmed-meshheading:15816526-Bone Neoplasms,
pubmed-meshheading:15816526-Cyclooxygenase 2,
pubmed-meshheading:15816526-Cyclooxygenase 2 Inhibitors,
pubmed-meshheading:15816526-Cyclooxygenase Inhibitors,
pubmed-meshheading:15816526-Dinoprostone,
pubmed-meshheading:15816526-Humans,
pubmed-meshheading:15816526-Male,
pubmed-meshheading:15816526-Membrane Proteins,
pubmed-meshheading:15816526-Mice,
pubmed-meshheading:15816526-Mice, SCID,
pubmed-meshheading:15816526-Osteoblasts,
pubmed-meshheading:15816526-Osteolysis,
pubmed-meshheading:15816526-Prostaglandin-Endoperoxide Synthases,
pubmed-meshheading:15816526-Prostatic Neoplasms,
pubmed-meshheading:15816526-Pyrazoles,
pubmed-meshheading:15816526-Sulfonamides
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pubmed:articleTitle |
The effect of cyclooxygenase-2 (COX-2) inhibition on human prostate cancer induced osteoblastic and osteolytic lesions in bone.
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pubmed:affiliation |
Department of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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