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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-1-28
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pubmed:abstractText |
Complement activation has been shown to play a significant role in ischemia-reperfusion injury after lung transplantation. TP-10 (soluble complement receptor 1 inhibitor) inhibits the activation of complement by inactivating C3a and C5a convertases. This was a clinical trial of TP-10 to reduce ischemia-reperfusion injury in lung transplantation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-5223
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
129
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
423-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15678055-Adolescent,
pubmed-meshheading:15678055-Adult,
pubmed-meshheading:15678055-Aged,
pubmed-meshheading:15678055-Biological Markers,
pubmed-meshheading:15678055-Cardiopulmonary Bypass,
pubmed-meshheading:15678055-Complement Inactivator Proteins,
pubmed-meshheading:15678055-Complement System Proteins,
pubmed-meshheading:15678055-Double-Blind Method,
pubmed-meshheading:15678055-Female,
pubmed-meshheading:15678055-Graft Rejection,
pubmed-meshheading:15678055-Humans,
pubmed-meshheading:15678055-Length of Stay,
pubmed-meshheading:15678055-Lung Diseases,
pubmed-meshheading:15678055-Lung Transplantation,
pubmed-meshheading:15678055-Male,
pubmed-meshheading:15678055-Middle Aged,
pubmed-meshheading:15678055-North America,
pubmed-meshheading:15678055-Oxygen Consumption,
pubmed-meshheading:15678055-Postoperative Complications,
pubmed-meshheading:15678055-Receptors, Complement,
pubmed-meshheading:15678055-Reperfusion Injury,
pubmed-meshheading:15678055-Respiration, Artificial,
pubmed-meshheading:15678055-Surgical Wound Infection,
pubmed-meshheading:15678055-Survival Analysis,
pubmed-meshheading:15678055-Treatment Outcome
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pubmed:year |
2005
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pubmed:articleTitle |
A randomized, placebo-controlled trial of complement inhibition in ischemia-reperfusion injury after lung transplantation in human beings.
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pubmed:affiliation |
University of Toronto, Toronto, Ontario, Canada. shaf.keshavjee@uhn.on.ca <shaf.keshavjee@uhn.on.ca>
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Multicenter Study
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