Linked Life Data

15638435

Source:http://linkedlifedata.com/resource/pubmed/id/15638435

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2005-1-10
pubmed:abstractText
S-100 is a structural protein of the central nervous system. An elevated level of S-100 in CSF is generally considered to be a marker of nervous tissue damage. The presence of this protein in blood serum points to the functional and/or morphological disruption of the blood-brain barrier. We measured S-100 in the cerebrospinal fluid and blood of children with two of the most often observed pathological states in child neurology--internal hydrocephalus and epilepsy. High levels of S-100 in CSF were detectable in children with internal hydrocephalus. Increased blood levels of S-100 protein were detectable in both groups of paediatric patients. Our preliminary results indicate neuronal damage in internal hydrocephalus and morphological and/or functional disturbances of the blood-brain barrier (their increased permeability) in both above mentioned disabilities.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:author
pubmed:volume
49 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
236-8
pubmed:dateRevised
2006-1-6
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
S-100 protein as marker of the blood-brain barrier disruption in children with internal hydrocephalus and epilepsy--a preliminary study.
pubmed:affiliation
Department of Child Neurology & Rehabilitation, Medical University of Bialystok, Poland. krsen@mp.pl
pubmed:publicationType
Journal Article