Regulated upon activation, normal T-cell expressed and secreted (RANTES) is a beta-chemokine and has been detected in brain lesions of multiple sclerosis (MS) patients. Considering its potential role in MS, we screened two functional polymorphisms in the proximal promoter region of the RANTES in MS patients versus controls.
Genetic Research Institute of the Desert, Eisenhower Medical Center, Probst # 308, 39000 Bob Hope Dr, Rancho Mirage, CA 92270, USA. randavolu@gridonline.org