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pubmed:abstractText |
DNA adenine methyltransferase (Dam) activity is absent in many, but not all, disease isolates of Neisseria meningitidis, as a consequence of the insertion of a restriction endonuclease-encoding gene, the 'dam replacing gene' (drg) at the dam locus. Here, we report the results of a survey to assess the prevalence of drg in a globally representative panel of disease-associated meningococci.
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pubmed:affiliation |
Peter Medawar Building for Pathogen Research, Department of Zoology, University of Oxford, South Parks Road, Oxford, OX1 3SY, UK. keith.jolley@medawar.ox.ac.uk
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