rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
2004-7-27
|
pubmed:abstractText |
Currently, there are various types of statins used in the treatment of hyperlipidemia and coronary artery disease. The purpose of this study was to compare the effects of a lipophilic statin (cerivastatin) with those of a hydrophilic statin (pravastatin) on the carotid arterial media using integrated backscatter (IB) ultrasound. Cerivastatin (C) has a strong anti-proliferative effect (APE) on smooth muscle cells (SMCs), whereas pravastatin (P) has a weak effect.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1346-9843
|
pubmed:author |
pubmed-author:AraiMasazumiM,
pubmed-author:FujiwaraHisayoshiH,
pubmed-author:ItoYokoY,
pubmed-author:KawasakiMasanoriM,
pubmed-author:MinatoguchiShinyaS,
pubmed-author:NishigakiKazuhikoK,
pubmed-author:OkuboMunenoriM,
pubmed-author:SanoKeijiK,
pubmed-author:TakemuraGenzouG,
pubmed-author:UnoYoshihiroY,
pubmed-author:YokoyamaHarukoH
|
pubmed:issnType |
Print
|
pubmed:volume |
68
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
784-90
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15277739-Aged,
pubmed-meshheading:15277739-Body Mass Index,
pubmed-meshheading:15277739-Carotid Arteries,
pubmed-meshheading:15277739-Female,
pubmed-meshheading:15277739-Humans,
pubmed-meshheading:15277739-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:15277739-Hyperlipidemias,
pubmed-meshheading:15277739-Lipids,
pubmed-meshheading:15277739-Male,
pubmed-meshheading:15277739-Middle Aged,
pubmed-meshheading:15277739-Pravastatin,
pubmed-meshheading:15277739-Pyridines,
pubmed-meshheading:15277739-Tunica Media
|
pubmed:year |
2004
|
pubmed:articleTitle |
Different effects of pravastatin and cerivastatin on the media of the carotid arteries as assessed by integrated backscatter ultrasound.
|
pubmed:affiliation |
Regeneration & Advanced Medical Science, Graduate School of Medicine, Gifu University, Japan.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|