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pubmed-article:15257098pubmed:abstractTextPrevious studies by our laboratory have demonstrated that parathyroid hormone-related protein (PTHrP) and its receptor (PTH/PTHrP receptor) are commonly expressed in pancreatic cancer and suggest their participation in the progression of this devastating disease. It has also been demonstrated that one of the major hallmarks of pancreatic adenocarcinoma is an increased production of the extracellular matrix (ECM), a critical regulator of diverse cellular processes such as differentiation, proliferation, and angiogenesis. The present study focused on the relationship between the PTHrP and ECM axes in the pathobiology of pancreatic cancer.lld:pubmed
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pubmed-article:15257098pubmed:articleTitleThe extracellular matrix differentially regulates the expression of PTHrP and the PTH/PTHrP receptor in FG pancreatic cancer cells.lld:pubmed
pubmed-article:15257098pubmed:affiliationDepartment of Surgery, University of California, San Diego and San Diego Veterans Affairs Medical Center, San Diego, California 92161, USA.lld:pubmed
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pubmed-article:15257098pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:15257098pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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