Source:http://linkedlifedata.com/resource/umls/id/C0070099
CSP: calcium-regulating hormone with endocrine, paracrine, and autocrine actions in bone; can cause hypercalcemia.,MSH: A ubiquitously expressed, secreted protein with bone resorption and renal calcium reabsorption activities that are similar to PARATHYROID HORMONE. It does not circulate in appreciable amounts in normal subjects, but rather exerts its biological actions locally. Overexpression of parathyroid hormone-related protein by tumor cells results in humoral calcemia of malignancy.,NCI: Parathyroid Hormone-Related protein signals through its receptor PTHR1, regulating endochondral bone development and epithelial-mesenchymal interactions. PTHRP is an anti-proliferative factor that regulates epidermal cell growth. Because of its structural homology with PTH and binding to the PTH/PTHRP receptor, PTHRP can mimic the action of PTH, but has evolved to regulate local tissue functions, in contrast to the systemic function of parathyroid hormone. To carry out its diverse biologic roles, PTHRP functions as a po