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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1992-10-9
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pubmed:abstractText |
This study compared prospectively viral culture for respiratory syncytial virus (RSV) with three rapid RSV antigen detection tests: RSV EIA and TestPack RSV (TP), and Directigen RSV (DIR). Additionally two methods of specimen collection were compared: nasopharyngeal rub (RUB) and nasopharyngeal wash (WASH). True positives were defined as positive RSV viral culture or at least two positive antigen tests. One hundred ninety-eight WASH specimens obtained from children 3 years of age or younger during the 1991 RSV winter epidemic were tested for RSV antigen. Sensitivity and specificity of WASH specimens were 59.5 and 100% (culture), 86.2 and 98.2% (RSV EIA), 91 and 96.3% (TP) and 83.5 and 94.3% (DIR). Concurrently obtained RUB samples from 124 children were tested by TP and/or DIR. Sensitivity of RUB specimens was significantly lower than that of WASH specimens; 64.9% (TP) and 43.6 (DIR). These easy to perform, rapid RSV antigen tests for WASH specimens provide timely diagnosis thereby facilitating management decisions and isolation efforts.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0891-3668
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
613-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1523070-Child, Preschool,
pubmed-meshheading:1523070-Humans,
pubmed-meshheading:1523070-Immunoenzyme Techniques,
pubmed-meshheading:1523070-Infant,
pubmed-meshheading:1523070-Nasopharyngeal Diseases,
pubmed-meshheading:1523070-Prospective Studies,
pubmed-meshheading:1523070-Reagent Kits, Diagnostic,
pubmed-meshheading:1523070-Respiratory Syncytial Viruses,
pubmed-meshheading:1523070-Respirovirus Infections
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pubmed:year |
1992
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pubmed:articleTitle |
Respiratory syncytial virus: a comparison of diagnostic modalities.
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pubmed:affiliation |
Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh, School of Medicine, PA 15213.
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pubmed:publicationType |
Journal Article,
Comparative Study
|