Linked Life Data

15131326

Source:http://linkedlifedata.com/resource/pubmed/id/15131326

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2004-5-7
pubmed:abstractText
The purpose of this chapter is to provide guidance to the novice investigator as to two models of ongoing nociception in rats. The models described herein are the formalin test, in which an irritant is injected subcutaneously into a dorsal paw and the numbers of flinches produced over 60 min are counted, and a mild burn model that produces a transitory primary and secondary thermal and mechanical hyperalgesia lasting approx 90 min. These models allow assessment of spinal sensitization, which may be an important factor when considering plasticity associated with human pain states. Detailed protocols using both manual and automated counting for the formalin test are included, as are methods concerning data analysis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1543-1894
pubmed:author
pubmed:issnType
Print
pubmed:volume
99
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
25-34
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Tissue injury models of persistent nociception in rats.
pubmed:affiliation
Department of Anesthesiology, University of California San Diego, La Jolla, USA.
pubmed:publicationType
Journal Article