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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2004-3-24
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pubmed:abstractText |
The prophylactic administration of antimicrobial agents to surgical patients has become standard practice to minimize the risk for postsurgical infection. During surgery, factors such as renal clearance, fluid administration, and blood loss contribute to drug concentrations achieved in the blood and tissues. The aminoglycoside gentamicin was chosen to investigate these factors because it is used for standard antimicrobial prophylaxis in colorectal surgery.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0149-2918
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
271-81
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:15038949-Adult,
pubmed-meshheading:15038949-Aged,
pubmed-meshheading:15038949-Aged, 80 and over,
pubmed-meshheading:15038949-Anti-Bacterial Agents,
pubmed-meshheading:15038949-Area Under Curve,
pubmed-meshheading:15038949-Blood Loss, Surgical,
pubmed-meshheading:15038949-Colorectal Surgery,
pubmed-meshheading:15038949-Female,
pubmed-meshheading:15038949-Fluid Therapy,
pubmed-meshheading:15038949-Gentamicins,
pubmed-meshheading:15038949-Greece,
pubmed-meshheading:15038949-Half-Life,
pubmed-meshheading:15038949-Humans,
pubmed-meshheading:15038949-Intraoperative Period,
pubmed-meshheading:15038949-Male,
pubmed-meshheading:15038949-Middle Aged,
pubmed-meshheading:15038949-Surgical Wound Infection,
pubmed-meshheading:15038949-Tissue Distribution
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pubmed:year |
2004
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pubmed:articleTitle |
Effects of blood loss and fluid volume replacement on serum and tissue gentamicin concentrations during colorectal surgery.
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pubmed:affiliation |
Laboratory of Biopharmaceutics and Pharmacokinetics, School of Pharmacy, University of Athens, Panepistimiopolis, Athens, Greece. kyroudi@pharm.uoa.gr
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pubmed:publicationType |
Journal Article
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