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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-3-12
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pubmed:abstractText |
Gut graft-versus-host disease (GVHD) contributes significantly to lethality after allogeneic hematopoietic stem-cell transplantation (HSCT). In murine models, macrophage secretion of interleukin 1alpha (IL-1alpha) and tumor necrosis factor alpha (TNF-alpha) contributes to gut GVHD pathogenesis. To help characterize whether human gut GVHD has similar biological characteristics, monocyte IL-1alpha and TNF-alpha production were evaluated after HSCT.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1542-3565
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
237-45
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pubmed:dateRevised |
2006-9-18
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pubmed:meshHeading |
pubmed-meshheading:15017608-Adult,
pubmed-meshheading:15017608-Aged,
pubmed-meshheading:15017608-Cell Movement,
pubmed-meshheading:15017608-Cytokines,
pubmed-meshheading:15017608-Disease Progression,
pubmed-meshheading:15017608-Female,
pubmed-meshheading:15017608-Flow Cytometry,
pubmed-meshheading:15017608-Graft vs Host Disease,
pubmed-meshheading:15017608-Hematologic Neoplasms,
pubmed-meshheading:15017608-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:15017608-Humans,
pubmed-meshheading:15017608-Interleukin-1,
pubmed-meshheading:15017608-Male,
pubmed-meshheading:15017608-Middle Aged,
pubmed-meshheading:15017608-Monocytes,
pubmed-meshheading:15017608-Prospective Studies,
pubmed-meshheading:15017608-Sensitivity and Specificity,
pubmed-meshheading:15017608-Severity of Illness Index,
pubmed-meshheading:15017608-Survival Analysis,
pubmed-meshheading:15017608-Transplantation, Homologous,
pubmed-meshheading:15017608-Tumor Markers, Biological,
pubmed-meshheading:15017608-Tumor Necrosis Factor-alpha
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pubmed:year |
2004
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pubmed:articleTitle |
Clinical "cytokine storm" as revealed by monocyte intracellular flow cytometry: correlation of tumor necrosis factor alpha with severe gut graft-versus-host disease.
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pubmed:affiliation |
Department of Experimental Transplantation and Immunology, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland 20892, USA. hfowler@helix.nih.gov
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pubmed:publicationType |
Journal Article
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