| pubmed-article:12883264 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12883264 | lifeskim:mentions | umls-concept:C2936598 | lld:lifeskim |
| pubmed-article:12883264 | lifeskim:mentions | umls-concept:C0000966 | lld:lifeskim |
| pubmed-article:12883264 | lifeskim:mentions | umls-concept:C0001962 | lld:lifeskim |
| pubmed-article:12883264 | lifeskim:mentions | umls-concept:C0752312 | lld:lifeskim |
| pubmed-article:12883264 | lifeskim:mentions | umls-concept:C1326120 | lld:lifeskim |
| pubmed-article:12883264 | lifeskim:mentions | umls-concept:C0086982 | lld:lifeskim |
| pubmed-article:12883264 | lifeskim:mentions | umls-concept:C0127400 | lld:lifeskim |
| pubmed-article:12883264 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:12883264 | pubmed:dateCreated | 2003-7-28 | lld:pubmed |
| pubmed-article:12883264 | pubmed:abstractText | Pancreatic fibrosis is a characteristic feature of alcoholic chronic pancreatitis. Recent studies suggest that activated pancreatic stellate cells (PSCs) are the major cell-type involved in pancreatic fibrogenesis. Cultured PSCs become activated when exposed to ethanol or its metabolite acetaldehyde (as indicated by increased alpha-smooth muscle actin [alpha-SMA] expression and increased collagen synthesis). However the intracellular signaling mechanisms responsible for ethanol- or acetaldehyde-induced PSC activation remain to be fully elucidated. One of the major signaling pathways known to regulate protein synthesis in mammalian cells is the mitogen-activated protein kinase (MARK) pathway. | lld:pubmed |
| pubmed-article:12883264 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:12883264 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12883264 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12883264 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:12883264 | pubmed:issn | 1536-4828 | lld:pubmed |
| pubmed-article:12883264 | pubmed:author | pubmed-author:WilsonJ SJS | lld:pubmed |
| pubmed-article:12883264 | pubmed:author | pubmed-author:ParkSS | lld:pubmed |
| pubmed-article:12883264 | pubmed:author | pubmed-author:PirolaR CRC | lld:pubmed |
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| pubmed-article:12883264 | pubmed:author | pubmed-author:PhillipsP APA | lld:pubmed |
| pubmed-article:12883264 | pubmed:author | pubmed-author:DohertyEE | lld:pubmed |
| pubmed-article:12883264 | pubmed:author | pubmed-author:McCarrollJ... | lld:pubmed |
| pubmed-article:12883264 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:12883264 | pubmed:volume | 27 | lld:pubmed |
| pubmed-article:12883264 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12883264 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12883264 | pubmed:pagination | 150-60 | lld:pubmed |
| pubmed-article:12883264 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:12883264 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12883264 | pubmed:articleTitle | Pancreatic stellate cell activation by ethanol and acetaldehyde: is it mediated by the mitogen-activated protein kinase signaling pathway? | lld:pubmed |
| pubmed-article:12883264 | pubmed:affiliation | Pancreatic Research Group, The University of New South Wales, Sydney, Australia. | lld:pubmed |
| pubmed-article:12883264 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12883264 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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