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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
15
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pubmed:dateCreated |
2003-7-18
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pubmed:abstractText |
[structure: see text] The first asymmetric total synthesis of a potential antitumor phenanthroindolizidine alkaloid, (-)-antofine, is described. An important feature of this synthesis is the creation of a stereogenic center by using enantioselective catalytic phase transfer alkylation, affording an unnatural alpha-amino acid derivative, together with a ring closing metathesis for pyrrolidine ring construction.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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|
pubmed:issn |
1523-7060
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
24
|
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pubmed:volume |
5
|
|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
2703-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
|
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pubmed:year |
2003
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pubmed:articleTitle |
First asymmetric total synthesis of (-)-antofine by using an enantioselective catalytic phase transfer alkylation.
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|
pubmed:affiliation |
College of Pharmacy, Seoul National University, San 56-1, Shilim, Kwanak, Seoul 151-742, Korea. pennkim@snu.ac.kr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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