Linked Life Data

12830872

Source:http://linkedlifedata.com/resource/pubmed/id/12830872

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2003-6-30
pubmed:abstractText
Electrostatic ion chromatography, also known as zwitterionic ion chromatography, has been predominantly used for the analysis of anions. Consequently, separation mechanisms proposed for this technique have been based on anion retention data obtained using a sulfobetaine-type surfactant-coated column. A comprehensive cation retention data set has been obtained on a C18 column coated with the zwitterionic surfactant N-tetradecylphosphocholine (which has the negatively and positively charged functional groups reversed in comparison to the sulfobetaine surfactants), with mobile phases being varied systematically in the concentration and species of both the mobile-phase anion and cation. A retention mechanism based on both an ion exclusion effect and a direct (chaotropic) interaction with the inner negative charge on the zwitterion is proposed for the retention of cations. Despite the relatively low chaotropic nature of cations compared with anions, the retention data shows that cations are retained in this system predominantly due to a chaotropic interaction with the inner charge, analogous to anions in a system where the C18 column is coated with a sulfobetaine-type surfactant. The retention of an analyte cation, and the effect of the mobile-phase anion and cation, can be predicted by the relative positions of these species on the Hofmeister (chaotropic) series.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0021-9673
pubmed:author
pubmed:issnType
Print
pubmed:day
16
pubmed:volume
997
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
13-20
pubmed:dateRevised
2009-1-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Mechanistic studies on the separation of cations in zwitterionic ion chromatography.
pubmed:affiliation
Australian Centre for Research on Separation Science, Department of Chemistry, University of Tasmania, Private Bag 75, Hobart, Tasmania 7001, Australia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't