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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2003-4-10
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pubmed:abstractText |
Arthritis in the K/BxN mouse model results from pathogenic immunoglobulins that recognize glucose-6-phosphate isomerase (GPI), a glycolytic enzyme residing in the cytoplasm of all cells. Antibodies directed against GPI can, alone, transfer arthritis to healthy recipients. Previous experiments have revealed significant titers of anti-GPI antibodies in the serum of many patients with rheumatoid arthritis (RA). We evaluated the generality of these observations in cohorts of patients with 12 different arthritic and chronic autoimmune diseases and in population-matched healthy control subjects.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0004-3591
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pubmed:author |
pubmed-author:AndersonRonald JRJ,
pubmed-author:BenoistChristopheC,
pubmed-author:BrennerMichaelM,
pubmed-author:CoblynJonathan SJS,
pubmed-author:DuclosBernardB,
pubmed-author:El-GabalawyHaniH,
pubmed-author:Goldbach-ManskyRaphaelaR,
pubmed-author:HitchonCarol ACA,
pubmed-author:LeeDavid MDM,
pubmed-author:MathisDianeD,
pubmed-author:MatsumotoIsaoI,
pubmed-author:PasqualiJean-LouisJL,
pubmed-author:SchurPeter HPH,
pubmed-author:SumidaTakayukiT,
pubmed-author:WeinblattMichael EME
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
944-54
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12687536-Adult,
pubmed-meshheading:12687536-Arthritis, Psoriatic,
pubmed-meshheading:12687536-Arthritis, Rheumatoid,
pubmed-meshheading:12687536-Autoantibodies,
pubmed-meshheading:12687536-Autoantigens,
pubmed-meshheading:12687536-Crohn Disease,
pubmed-meshheading:12687536-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:12687536-Female,
pubmed-meshheading:12687536-Glucose-6-Phosphate Isomerase,
pubmed-meshheading:12687536-Humans,
pubmed-meshheading:12687536-Lupus Erythematosus, Systemic,
pubmed-meshheading:12687536-Male,
pubmed-meshheading:12687536-Middle Aged,
pubmed-meshheading:12687536-Recombinant Proteins,
pubmed-meshheading:12687536-Sarcoidosis,
pubmed-meshheading:12687536-Spondylitis, Ankylosing
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pubmed:year |
2003
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pubmed:articleTitle |
Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders.
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pubmed:affiliation |
Joslin Diabetes Center and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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