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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2003-3-25
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pubmed:abstractText |
HER2 protein is over-expressed in 15-30% of breast carcinomas. Immunohistochemistry (IHC) is a common and inexpensive method able to specifically detect HER2 protein. However, lack of standardization of IHC has been considered responsible for discrepancies in HER2 status assessment performed by IHC and fluorescence in-situ hybridization (FISH). This prompted us to perform a multicentric IHC calibration test to achieve a maximum accuracy of HER2-IHC compared with HER2-FISH taken as the reference method.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0309-0167
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pubmed:author |
pubmed-author:ArnouldLL,
pubmed-author:CouturierJJ,
pubmed-author:DenouxYY,
pubmed-author:FicheMM,
pubmed-author:JacquemierJJ,
pubmed-author:Le DoussalVV,
pubmed-author:MacGroganGG,
pubmed-author:MathieuM-CMC,
pubmed-author:Mathoulin-PélissierSS,
pubmed-author:Penault-LlorcaFF,
pubmed-author:RigaudCC,
pubmed-author:RogerPP,
pubmed-author:TreilleuxII,
pubmed-author:VilainM-OMO,
pubmed-author:Vincent-SalomonAA
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pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
337-47
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12653945-Adenocarcinoma,
pubmed-meshheading:12653945-Adult,
pubmed-meshheading:12653945-Aged,
pubmed-meshheading:12653945-Aged, 80 and over,
pubmed-meshheading:12653945-Breast Neoplasms,
pubmed-meshheading:12653945-Female,
pubmed-meshheading:12653945-Genes, erbB-2,
pubmed-meshheading:12653945-Humans,
pubmed-meshheading:12653945-Immunohistochemistry,
pubmed-meshheading:12653945-In Situ Hybridization, Fluorescence,
pubmed-meshheading:12653945-Middle Aged,
pubmed-meshheading:12653945-Neoplasm Staging,
pubmed-meshheading:12653945-Receptor, erbB-2,
pubmed-meshheading:12653945-Reproducibility of Results,
pubmed-meshheading:12653945-Sensitivity and Specificity
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pubmed:year |
2003
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pubmed:articleTitle |
Calibration of immunohistochemistry for assessment of HER2 in breast cancer: results of the French multicentre GEFPICS study.
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pubmed:affiliation |
Institut Curie, Paris, France. anne.salomon@curie.net
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
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