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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2001-12-17
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pubmed:abstractText |
The JAK/STAT signal transduction pathway plays a critical role in mammalian cells, particularly in hematopoiesis and immune responses. Several components of this pathway have been identified and characterized in Drosophila. Mutational analyses of these components have revealed a number of interesting developmental roles, and provide a mechanism to identify other interacting molecules and pathways. Hence, the JAK/STAT pathway in Drosophila serves as an attractive model for in vivo functional analyses of JAK/STAT signaling.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Drosophila Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Insect Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Janus Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/STAT Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Stat92E protein, Drosophila,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/hopscotch protein, Drosophila,
http://linkedlifedata.com/resource/pubmed/chemical/os protein, Drosophila
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0265-9247
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2001 John Wiley & Sons, Inc.
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pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1138-47
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:11746233-Animals,
pubmed-meshheading:11746233-DNA-Binding Proteins,
pubmed-meshheading:11746233-Drosophila,
pubmed-meshheading:11746233-Drosophila Proteins,
pubmed-meshheading:11746233-Extremities,
pubmed-meshheading:11746233-Eye,
pubmed-meshheading:11746233-Glycoproteins,
pubmed-meshheading:11746233-Insect Proteins,
pubmed-meshheading:11746233-Janus Kinases,
pubmed-meshheading:11746233-Protein-Tyrosine Kinases,
pubmed-meshheading:11746233-STAT Transcription Factors,
pubmed-meshheading:11746233-Sex Determination Processes,
pubmed-meshheading:11746233-Signal Transduction,
pubmed-meshheading:11746233-Trans-Activators,
pubmed-meshheading:11746233-Transcription Factors,
pubmed-meshheading:11746233-Wing
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pubmed:year |
2001
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pubmed:articleTitle |
The JAK/STAT pathway and Drosophila development.
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pubmed:affiliation |
The Cardiovascular Research Institute, Division of Molecular Cardiology, The Texas A&M University System Health Science Center, College of Medicine, Temple, Texas 76504, USA. hluo@medicine.tamu.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
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