| pubmed-article:11294672 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11294672 | lifeskim:mentions | umls-concept:C0014051 | lld:lifeskim |
| pubmed-article:11294672 | lifeskim:mentions | umls-concept:C0035236 | lld:lifeskim |
| pubmed-article:11294672 | lifeskim:mentions | umls-concept:C0029347 | lld:lifeskim |
| pubmed-article:11294672 | lifeskim:mentions | umls-concept:C0035668 | lld:lifeskim |
| pubmed-article:11294672 | lifeskim:mentions | umls-concept:C0042210 | lld:lifeskim |
| pubmed-article:11294672 | lifeskim:mentions | umls-concept:C1545588 | lld:lifeskim |
| pubmed-article:11294672 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:11294672 | pubmed:dateCreated | 2001-4-11 | lld:pubmed |
| pubmed-article:11294672 | pubmed:abstractText | In genetic vaccination, recipients are immunized with antigen-encoding nucleic acid, usually DNA. This study addressed the possibility of using the recombinant alpha virus RNA molecule, which replicates in the cytoplasm of transfected cells, as a novel approach for genetic vaccination. Mice were immunized with recombinant Semliki Forest virus RNA-encoding envelope proteins from one of 3 viruses: influenza A virus, a tickborne flavivirus (louping ill virus), or respiratory syncytial virus (RSV). Serologic analyses showed that antigen-specific antibody responses were elicited. IgG isotyping indicated that predominantly Th1 type immune responses were induced after immunization with RSV F protein-encoding RNA, which is relevant for protection against RSV infection. Challenge infection showed that RNA immunization had elicited significant levels of protection against the 3 model virus diseases. | lld:pubmed |
| pubmed-article:11294672 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11294672 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11294672 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:11294672 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11294672 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11294672 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11294672 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11294672 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11294672 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11294672 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11294672 | pubmed:month | May | lld:pubmed |
| pubmed-article:11294672 | pubmed:issn | 0022-1899 | lld:pubmed |
| pubmed-article:11294672 | pubmed:author | pubmed-author:MurphyMM | lld:pubmed |
| pubmed-article:11294672 | pubmed:author | pubmed-author:ChenMM | lld:pubmed |
| pubmed-article:11294672 | pubmed:author | pubmed-author:RhodesGG | lld:pubmed |
| pubmed-article:11294672 | pubmed:author | pubmed-author:AtkinsG JGJ | lld:pubmed |
| pubmed-article:11294672 | pubmed:author | pubmed-author:ParkerS ESE | lld:pubmed |
| pubmed-article:11294672 | pubmed:author | pubmed-author:LiljeströmPP | lld:pubmed |
| pubmed-article:11294672 | pubmed:author | pubmed-author:BerglundPP | lld:pubmed |
| pubmed-article:11294672 | pubmed:author | pubmed-author:FleetonM NMN | lld:pubmed |
| pubmed-article:11294672 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11294672 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:11294672 | pubmed:volume | 183 | lld:pubmed |
| pubmed-article:11294672 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11294672 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11294672 | pubmed:pagination | 1395-8 | lld:pubmed |
| pubmed-article:11294672 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:11294672 | pubmed:meshHeading | pubmed-meshheading:11294672... | lld:pubmed |
| pubmed-article:11294672 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11294672 | pubmed:articleTitle | Self-replicative RNA vaccines elicit protection against influenza A virus, respiratory syncytial virus, and a tickborne encephalitis virus. | lld:pubmed |
| pubmed-article:11294672 | pubmed:affiliation | Microbiology and Tumorbiology Center, Karolinska Institutet, S-171 77 Stockholm, Sweden. | lld:pubmed |
| pubmed-article:11294672 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11294672 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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