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rdf:type |
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lifeskim:mentions |
umls-concept:C0001047,
umls-concept:C0013072,
umls-concept:C0023884,
umls-concept:C0023981,
umls-concept:C0030705,
umls-concept:C0034656,
umls-concept:C0036983,
umls-concept:C0232338,
umls-concept:C0232741,
umls-concept:C0332161,
umls-concept:C0442805,
umls-concept:C1274040
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pubmed:issue |
12
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pubmed:dateCreated |
2001-1-10
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pubmed:abstractText |
In septic shock, decreased splanchnic blood flow is reported, despite adequate systemic hemodynamics. Aacetylcysteine (NAC) was found to increase hepatosplanchnic blood flow in experimental settings. In septic shock patients, NAC improved the clearance of indocyanine green and the relationship of systemic oxygen consumption to oxygen demand. We investigated the influence of NAC on liver blood flow, hepatosplanchnic oxygen transport-related variables, and liver function during early septic shock.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0090-3493
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3799-807
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11153617-Acetylcysteine,
pubmed-meshheading:11153617-Adult,
pubmed-meshheading:11153617-Aged,
pubmed-meshheading:11153617-Blood Flow Velocity,
pubmed-meshheading:11153617-Coloring Agents,
pubmed-meshheading:11153617-Double-Blind Method,
pubmed-meshheading:11153617-Female,
pubmed-meshheading:11153617-Free Radical Scavengers,
pubmed-meshheading:11153617-Hemodynamics,
pubmed-meshheading:11153617-Humans,
pubmed-meshheading:11153617-Indocyanine Green,
pubmed-meshheading:11153617-Infusions, Intravenous,
pubmed-meshheading:11153617-Injections, Intravenous,
pubmed-meshheading:11153617-Lidocaine,
pubmed-meshheading:11153617-Liver,
pubmed-meshheading:11153617-Liver Circulation,
pubmed-meshheading:11153617-Liver Function Tests,
pubmed-meshheading:11153617-Male,
pubmed-meshheading:11153617-Metabolic Clearance Rate,
pubmed-meshheading:11153617-Microsomes, Liver,
pubmed-meshheading:11153617-Middle Aged,
pubmed-meshheading:11153617-Oxygen Consumption,
pubmed-meshheading:11153617-Prospective Studies,
pubmed-meshheading:11153617-Shock, Septic,
pubmed-meshheading:11153617-Survival Analysis
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pubmed:year |
2000
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pubmed:articleTitle |
N-acetylcysteine increases liver blood flow and improves liver function in septic shock patients: results of a prospective, randomized, double-blind study.
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pubmed:affiliation |
Department of Anesthesiology and Operative Intensive Care Medicine, University Hospital Benjamin Franklin, Freie Universität Berlin, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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