Linked Life Data

1111573

Source:http://linkedlifedata.com/resource/pubmed/id/1111573

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1975-5-10
pubmed:abstractText
Temperature-jump experiments on isolated myelinated nerve fibers were done using a pulsed laser system in the Q switched mode. Voltage-clamp and temperature perturbations were used to measure the relaxing ionic conductances of both the Na+ and K+ systems. It is shown that the T jump can be used to probe the K+ and Na+ conductances during non-steady state conditions and thereby elicit relaxation times for a variety of initial states. Temperature-induced K+ conductance relaxation times were consistent with voltage-clamp measurements. The temperature-perturbation experiments were done as a combination of a temperature step and impulse change due to an adsorption of carbon black particles on the nerve. The experiments support the hypothesis that the relaxation times of the K+ system are independent of the previous history of the axon. It is concluded that the K+ conductance is at least a second-order system whose relaxation spectrum is composed of two exponential terms the magnitudes of which are markedly dependent on the initial conditions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
375
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
115-23
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Membrane conductance changes in single nodes of Ranvier, measured by laser-induced temperature-jump experiments.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.