|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
17
|
|
pubmed:dateCreated |
2000-10-3
|
|
pubmed:abstractText |
The Drosophila tracheal system, a tubular network, is formed from isolated ectodermal metameres by guided branch outgrowth and branch fusion. Branch outgrowth is triggered by the localized and transient activity of Branchless (Bnl/dFGF). Here, we report the discovery of a mesodermal cell that links the leading cells of outgrowing main branches 2.5 hr before they fuse. This bridge-cell serves as an essential guidance post and needs Hunchback (Hb) activity to exert its function. The bridge-cell provides cues acting in concert with Bnl/dFGF signaling to mediate directed branch outgrowth that ultimately leads to position-specific branch fusion.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-10383344,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-1571289,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-1651183,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-2065664,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-2199063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-7905822,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-7925015,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-8096627,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-8125257,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-8223268,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-8365569,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-8557189,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-8557198,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-8625828,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-8681802,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-8918892,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-8978613,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-9109485,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10970878-9598358
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Drosophila Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Insect Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Oligonucleotides, Antisense,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/beta-Galactosidase,
http://linkedlifedata.com/resource/pubmed/chemical/branchless protein, Drosophila,
http://linkedlifedata.com/resource/pubmed/chemical/hunchback protein, Drosophila
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0890-9369
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
1
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2140-5
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:10970878-Animals,
pubmed-meshheading:10970878-Apoptosis,
pubmed-meshheading:10970878-DNA-Binding Proteins,
pubmed-meshheading:10970878-Drosophila,
pubmed-meshheading:10970878-Drosophila Proteins,
pubmed-meshheading:10970878-Ectoderm,
pubmed-meshheading:10970878-Fibroblast Growth Factors,
pubmed-meshheading:10970878-Immunohistochemistry,
pubmed-meshheading:10970878-In Situ Hybridization,
pubmed-meshheading:10970878-In Situ Nick-End Labeling,
pubmed-meshheading:10970878-Insect Proteins,
pubmed-meshheading:10970878-Mesoderm,
pubmed-meshheading:10970878-Microscopy, Confocal,
pubmed-meshheading:10970878-Mutagenesis,
pubmed-meshheading:10970878-Oligonucleotides, Antisense,
pubmed-meshheading:10970878-Signal Transduction,
pubmed-meshheading:10970878-Time Factors,
pubmed-meshheading:10970878-Trachea,
pubmed-meshheading:10970878-Transcription Factors,
pubmed-meshheading:10970878-beta-Galactosidase
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Single mesodermal cells guide outgrowth of ectodermal tubular structures in Drosophila.
|
|
pubmed:affiliation |
Max Planck Institut für biophysikalische Chemie, Abteilung Molekulare Entwicklungsbiologie, Am Fassberg, D-37077 Göttingen, Germany.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
