|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2000-7-19
|
|
pubmed:abstractText |
Multiple quantifiable biologic abnormalities have been localized to the hippocampus in schizophrenia. Alterations in glutamate-mediated transmission at N-methyl-D-aspartic acid (NMDA)-sensitive receptors in hippocampus have been implicated in the pathophysiology of the illness. The authors tested the hypothesis that glutamatergic transmission within and efferent from hippocampus is altered in schizophrenia.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antipsychotic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, AMPA,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Glutamate,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Kainic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, N-Methyl-D-Aspartate
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0002-953X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
157
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1141-9
|
|
pubmed:dateRevised |
2004-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:10873924-Adult,
pubmed-meshheading:10873924-Animals,
pubmed-meshheading:10873924-Antipsychotic Agents,
pubmed-meshheading:10873924-Autoradiography,
pubmed-meshheading:10873924-Female,
pubmed-meshheading:10873924-Hippocampus,
pubmed-meshheading:10873924-Humans,
pubmed-meshheading:10873924-In Situ Hybridization,
pubmed-meshheading:10873924-Male,
pubmed-meshheading:10873924-Middle Aged,
pubmed-meshheading:10873924-RNA, Messenger,
pubmed-meshheading:10873924-Radioligand Assay,
pubmed-meshheading:10873924-Rats,
pubmed-meshheading:10873924-Receptors, AMPA,
pubmed-meshheading:10873924-Receptors, Glutamate,
pubmed-meshheading:10873924-Receptors, Kainic Acid,
pubmed-meshheading:10873924-Receptors, N-Methyl-D-Aspartate,
pubmed-meshheading:10873924-Schizophrenia
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia.
|
|
pubmed:affiliation |
Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD 21228, USA.
|
|
pubmed:publicationType |
Journal Article
|
