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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2000-5-11
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pubmed:abstractText |
There is increasing evidence that eotaxin is a key mediator in the development of tissue eosinophilia. However, the mechanism involved in the production of eotaxin has yet to be clarified. Most recently, it has been shown that interleukin (IL) -4 induces eotaxin in dermal fibroblasts. A novel cytokine termed IL-13, which binds to the alpha-chain of the IL-4 receptor, shares many biological activities with IL-4. It is known that fibroblasts express the IL-4 receptor and produce collagen type I upon stimulation with IL-4.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Allergens,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Dermatophagoides,
http://linkedlifedata.com/resource/pubmed/chemical/CCL11 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL11,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CC,
http://linkedlifedata.com/resource/pubmed/chemical/Chemotactic Factors, Eosinophil,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-13,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-4,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0954-7894
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
348-55
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:10691892-Adult,
pubmed-meshheading:10691892-Allergens,
pubmed-meshheading:10691892-Animals,
pubmed-meshheading:10691892-Antigens, Dermatophagoides,
pubmed-meshheading:10691892-Chemokine CCL11,
pubmed-meshheading:10691892-Chemokines, CC,
pubmed-meshheading:10691892-Chemotactic Factors, Eosinophil,
pubmed-meshheading:10691892-Cytokines,
pubmed-meshheading:10691892-Dose-Response Relationship, Drug,
pubmed-meshheading:10691892-Drug Synergism,
pubmed-meshheading:10691892-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:10691892-Female,
pubmed-meshheading:10691892-Fibroblasts,
pubmed-meshheading:10691892-Glycoproteins,
pubmed-meshheading:10691892-Humans,
pubmed-meshheading:10691892-Interleukin-13,
pubmed-meshheading:10691892-Interleukin-4,
pubmed-meshheading:10691892-Male,
pubmed-meshheading:10691892-Mites,
pubmed-meshheading:10691892-Nasal Mucosa,
pubmed-meshheading:10691892-RNA, Messenger,
pubmed-meshheading:10691892-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:10691892-Rhinitis, Allergic, Perennial,
pubmed-meshheading:10691892-Tumor Necrosis Factor-alpha
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pubmed:year |
2000
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pubmed:articleTitle |
Interleukin-13 and tumour necrosis factor-alpha synergistically induce eotaxin production in human nasal fibroblasts.
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pubmed:affiliation |
Department of Otorhinolaryngology, Chiba University School of Medicine, Chiba, Japan. terada@med.m.chiba-u.ac.jp
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pubmed:publicationType |
Journal Article
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