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rdf:type |
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lifeskim:mentions |
umls-concept:C0040300,
umls-concept:C0123759,
umls-concept:C0175677,
umls-concept:C0205082,
umls-concept:C0242632,
umls-concept:C0871261,
umls-concept:C1179187,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1999177,
umls-concept:C2911692
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pubmed:issue |
5
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pubmed:dateCreated |
1999-12-8
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pubmed:abstractText |
Interleukin (IL)-12 is believed to modulate local T-cell response in human colitis. A direct functional relationship between IL-12 and tissue injury in human intestine has not been reported. The aim of this study was to examine changes that take place in explant cultures of human fetal gut after stimulation of T cells with anti-CD3 in the presence of exogenous IL-12/IL-18.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Collagenases,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/IL18R1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-12,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-18,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-18 Receptor alpha...,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Isoforms,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-12,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-18,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor...,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Fusion Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1069-77
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10535869-Antigens, CD,
pubmed-meshheading:10535869-Collagenases,
pubmed-meshheading:10535869-Cytokines,
pubmed-meshheading:10535869-Fetus,
pubmed-meshheading:10535869-Humans,
pubmed-meshheading:10535869-Interleukin-12,
pubmed-meshheading:10535869-Interleukin-18,
pubmed-meshheading:10535869-Interleukin-18 Receptor alpha Subunit,
pubmed-meshheading:10535869-Intestinal Mucosa,
pubmed-meshheading:10535869-Intestines,
pubmed-meshheading:10535869-Matrix Metalloproteinase 3,
pubmed-meshheading:10535869-Organ Culture Techniques,
pubmed-meshheading:10535869-Protein Isoforms,
pubmed-meshheading:10535869-Proteins,
pubmed-meshheading:10535869-Receptors, Interleukin,
pubmed-meshheading:10535869-Receptors, Interleukin-12,
pubmed-meshheading:10535869-Receptors, Interleukin-18,
pubmed-meshheading:10535869-Receptors, Tumor Necrosis Factor,
pubmed-meshheading:10535869-Receptors, Tumor Necrosis Factor, Type I,
pubmed-meshheading:10535869-Recombinant Fusion Proteins,
pubmed-meshheading:10535869-Th1 Cells
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pubmed:year |
1999
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pubmed:articleTitle |
Enhancing Lamina propria Th1 cell responses with interleukin 12 produces severe tissue injury.
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pubmed:affiliation |
Department of Paediatric Gastroenterology, St. Bartholomew's and the Royal London School of Medicine and Dentistry, London, England.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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