Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions |
umls-concept:C0001629,
umls-concept:C0024400,
umls-concept:C0025148,
umls-concept:C0034229,
umls-concept:C0205092,
umls-concept:C0205155,
umls-concept:C0205197,
umls-concept:C0441889,
umls-concept:C1160858,
umls-concept:C1522472,
umls-concept:C1550278,
umls-concept:C1551341,
umls-concept:C1552858,
umls-concept:C1552923,
umls-concept:C1552924,
umls-concept:C1705191
|
| pubmed:issue |
3
|
| pubmed:dateCreated |
1979-1-15
|
| pubmed:abstractText |
Ten Macaca mulatta monkeys were operantly conditioned to perform three motor paradigms designed to evaluate single and combination finger movements. Eight of these monkeys were retested after left medullary pyramidotomy; 2 monkeys underwent left medullary pyramidotomy prior to conditioning. All animals were tested for three years after operation. Monkeys with a completely sectioned medullary pyramid could, with time, perform difficult motor paradigms that required: (1) both individual and combination finger movements; (2) proximal upper extremity motor control; (3) thumb and index finger pincer grasp; and (4) the ability to preprogram and then execute a precision hand movement. The greater the extent of pyramidal tract destruction, the longer the time necessary for recovery of both discrete finger movement and pincer grasp, the greater the effort needed to attain recovery of hand function, and the weaker the affected musculature. The 2 animals in which pyramidotomy of at least 70% of the tract preceded efforts at operant conditioning learned and performed difficult motor paradigms. In all animals, neurological examination revealed that the most enduring and functionally most important deficit that interferes with hand function following pyramidotomy is loss of contactual hand orienting responses and failure of reflex sensorimotor adjustments.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0364-5134
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
4
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
234-44
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:102241-Animals,
pubmed-meshheading:102241-Behavior, Animal,
pubmed-meshheading:102241-Hand,
pubmed-meshheading:102241-Haplorhini,
pubmed-meshheading:102241-Macaca mulatta,
pubmed-meshheading:102241-Male,
pubmed-meshheading:102241-Medulla Oblongata,
pubmed-meshheading:102241-Movement,
pubmed-meshheading:102241-Pyramidal Tracts
|
| pubmed:year |
1978
|
| pubmed:articleTitle |
A behavioral analysis of complete unilateral section of the pyramidal tract at the medullary level in Macaca mulatta.
|
| pubmed:publicationType |
Journal Article
|