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pubmed-article:10079035pubmed:abstractTextExpression of leptin receptor (OB-R) mRNA was detected in the human anterior pituitary as well as in ACTH-secreting and nonsecreting pituitary adenomas by RT-PCR with primers recognizing all receptor splice variants. Primers specific to the long splice variant of the leptin receptor (OB-Rb), containing the putative intracellular signalling domain, also revealed a strong expression in normal and adenomatous anterior pituitaries. These results indicate that the pituitary is a possible target tissue of leptin action and might be involved in leptin regulation of pituitary hormone secretion.lld:pubmed
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pubmed-article:10079035pubmed:dateRevised2008-11-21lld:pubmed
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pubmed-article:10079035pubmed:articleTitleExpression of leptin receptor mRNA and the long form splice variant in human anterior pituitary and pituitary adenoma.lld:pubmed
pubmed-article:10079035pubmed:affiliationDept. of Endocrinology and Metabolism, University Hospital Magdeburg, Germany.lld:pubmed
pubmed-article:10079035pubmed:publicationTypeJournal Articlelld:pubmed
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