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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
6
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pubmed:dateCreated |
1999-4-30
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pubmed:abstractText |
Expression of leptin receptor (OB-R) mRNA was detected in the human anterior pituitary as well as in ACTH-secreting and nonsecreting pituitary adenomas by RT-PCR with primers recognizing all receptor splice variants. Primers specific to the long splice variant of the leptin receptor (OB-Rb), containing the putative intracellular signalling domain, also revealed a strong expression in normal and adenomatous anterior pituitaries. These results indicate that the pituitary is a possible target tissue of leptin action and might be involved in leptin regulation of pituitary hormone secretion.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:issn |
0947-7349
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
106
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|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
522-5
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pubmed:dateRevised |
2008-11-21
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|
pubmed:meshHeading |
pubmed-meshheading:10079035-Adenoma,
pubmed-meshheading:10079035-Adrenocorticotropic Hormone,
pubmed-meshheading:10079035-Adult,
pubmed-meshheading:10079035-Aged,
pubmed-meshheading:10079035-Carrier Proteins,
pubmed-meshheading:10079035-Female,
pubmed-meshheading:10079035-Gene Expression,
pubmed-meshheading:10079035-Genetic Variation,
pubmed-meshheading:10079035-Humans,
pubmed-meshheading:10079035-Male,
pubmed-meshheading:10079035-Middle Aged,
pubmed-meshheading:10079035-Pituitary Gland, Anterior,
pubmed-meshheading:10079035-Pituitary Neoplasms,
pubmed-meshheading:10079035-RNA, Messenger,
pubmed-meshheading:10079035-RNA Splicing,
pubmed-meshheading:10079035-Receptors, Cell Surface,
pubmed-meshheading:10079035-Receptors, Leptin
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pubmed:year |
1998
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|
pubmed:articleTitle |
Expression of leptin receptor mRNA and the long form splice variant in human anterior pituitary and pituitary adenoma.
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pubmed:affiliation |
Dept. of Endocrinology and Metabolism, University Hospital Magdeburg, Germany.
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pubmed:publicationType |
Journal Article
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