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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1999-2-24
|
| pubmed:abstractText |
The correlation between tumor microsatellite instability (MSI) and the accumulation of mutations in KRAS2 and TP53 is uncertain. The authors evaluated the TP53 and KRAS2 genes for mutations in sporadic endometrial carcinomas with microsatellite instability (MSI) and matched MSI negative controls to determine whether defective DNA mismatch repair impacts the patterns of mutations in two genes known to be involved in endometrial tumorigenesis.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0008-543X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
85
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
119-26
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9921983-DNA Repair,
pubmed-meshheading:9921983-Endometrial Neoplasms,
pubmed-meshheading:9921983-Female,
pubmed-meshheading:9921983-Genes, p53,
pubmed-meshheading:9921983-Humans,
pubmed-meshheading:9921983-Microsatellite Repeats,
pubmed-meshheading:9921983-Mutation,
pubmed-meshheading:9921983-Polymerase Chain Reaction,
pubmed-meshheading:9921983-Prognosis,
pubmed-meshheading:9921983-Proto-Oncogene Proteins,
pubmed-meshheading:9921983-ras Proteins
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Differences in patterns of TP53 and KRAS2 mutations in a large series of endometrial carcinomas with or without microsatellite instability.
|
| pubmed:affiliation |
Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|