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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1999-4-13
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pubmed:abstractText |
Matrix metalloproteinases play a critical role in fetal membrane extracellular matrix (ECM) homeostasis. Remodeling of the ECM during normal placental development is a balanced activity between various matrix metalloproteinases and their tissue-specific counter-regulatory proteins (tissue inhibitors of matrix metalloproteinases [TIMPs]). We have reported the presence of TIMP-1 and TIMP-2 in placental membranes in culture. In this study we have investigated the membrane expression of TIMP-1 and TIMP-2 during labor and nonlabor conditions and also the presence of two novel TIMP family members (TIMP-3 and TIMP-4).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1046-7408
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
395-400
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pubmed:dateRevised |
2006-10-12
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pubmed:meshHeading |
pubmed-meshheading:9894562-Extraembryonic Membranes,
pubmed-meshheading:9894562-Female,
pubmed-meshheading:9894562-Fetal Membranes, Premature Rupture,
pubmed-meshheading:9894562-Humans,
pubmed-meshheading:9894562-In Situ Hybridization,
pubmed-meshheading:9894562-Labor, Obstetric,
pubmed-meshheading:9894562-Organ Culture Techniques,
pubmed-meshheading:9894562-Pregnancy,
pubmed-meshheading:9894562-RNA, Messenger,
pubmed-meshheading:9894562-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:9894562-Tissue Inhibitor of Metalloproteinase-1,
pubmed-meshheading:9894562-Tissue Inhibitor of Metalloproteinase-2,
pubmed-meshheading:9894562-Tissue Inhibitor of Metalloproteinase-3,
pubmed-meshheading:9894562-Tissue Inhibitor of Metalloproteinases
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pubmed:year |
1998
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pubmed:articleTitle |
Presence of four tissue inhibitors of matrix metalloproteinases (TIMP-1, -2, -3 and -4) in human fetal membranes.
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pubmed:affiliation |
Maternal Fetal Group, Women's Health Research and Education Foundation, Nashville, Tennessee, USA.
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pubmed:publicationType |
Journal Article
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