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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
19
|
| pubmed:dateCreated |
1999-2-2
|
| pubmed:abstractText |
A series of nonsteroidal human progesterone receptor (hPR) antagonists based on conformationally-restricted analogues of a 6-aryl-1,2-dihydro-2,2,4-trimethylquinoline pharmacophore were synthesized and evaluated for their ability to bind to the human progesterone receptor and inhibit progesterone-stimulated reporter gene expression in mammalian cells.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0960-894X
|
| pubmed:author |
pubmed-author:EdwardsJ PJP,
pubmed-author:FarmerL JLJ,
pubmed-author:GoldmanM EME,
pubmed-author:HamannL GLG,
pubmed-author:JonesT KTK,
pubmed-author:MaisD EDE,
pubmed-author:MarschkeK BKB,
pubmed-author:PooleyC LCL,
pubmed-author:TegleyC MCM,
pubmed-author:WestS JSJ,
pubmed-author:WinkD ADA,
pubmed-author:ZhiLL
|
| pubmed:issnType |
Print
|
| pubmed:day |
6
|
| pubmed:volume |
8
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
2731-6
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading | |
| pubmed:year |
1998
|
| pubmed:articleTitle |
Nonsteroidal progesterone receptor antagonists based on a conformationally-restricted subseries of 6-aryl-1,2-dihydro-2,2,4-trimethylquinolines.
|
| pubmed:affiliation |
Department of Medicinal Chemistry, Ligand Pharmaceuticals, San Diego, CA 92121, USA.
|
| pubmed:publicationType |
Journal Article
|