rdf:type |
|
lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0027627,
umls-concept:C0029463,
umls-concept:C0033684,
umls-concept:C0205263,
umls-concept:C0243077,
umls-concept:C0332281,
umls-concept:C0380603,
umls-concept:C0443264,
umls-concept:C0600251,
umls-concept:C0623362,
umls-concept:C1419786
|
pubmed:issue |
5A
|
pubmed:dateCreated |
1998-12-29
|
pubmed:abstractText |
Several recent investigations have shown that the expression of the CAPL protein seems to be of importance in the metastatic potential in some types of cancer. However, the mechanisms behind this and other biological functions of CAPL are still largely unknown. The aim of the present work was to investigate whether CAPL could affect the expression of candidate proteolytic facilitators of the metastatic process, i.e. matrix metalloproteinases (MMPs) and their inhibitors (TIMPs).
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0250-7005
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3299-303
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9858899-Bone Neoplasms,
pubmed-meshheading:9858899-Collagenases,
pubmed-meshheading:9858899-Enzyme Induction,
pubmed-meshheading:9858899-Fibroblast Growth Factor 2,
pubmed-meshheading:9858899-Humans,
pubmed-meshheading:9858899-Interleukin-1,
pubmed-meshheading:9858899-Matrix Metalloproteinase 1,
pubmed-meshheading:9858899-Neoplasm Invasiveness,
pubmed-meshheading:9858899-Neoplasm Proteins,
pubmed-meshheading:9858899-Osteosarcoma,
pubmed-meshheading:9858899-S100 Proteins,
pubmed-meshheading:9858899-Tissue Inhibitor of Metalloproteinase-1,
pubmed-meshheading:9858899-Tumor Cells, Cultured
|
pubmed:articleTitle |
Interleukin-1 alpha and basic fibroblast growth factor induction of matrix metalloproteinases and their inhibitors in osteosarcoma cells is modulated by the metastasis associated protein CAPL.
|
pubmed:affiliation |
Department of Biochemistry, Institute of Medical Biology, Tromsø, Norway.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|