Source:http://linkedlifedata.com/resource/umls/id/C0600251
NCI: One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-1-alpha, one form of IL-1, is made mainly by one type of white blood cell, the macrophage, and helps another type of white blood cell, the lymphocyte, fight infections. It also helps leukocytes pass through blood vessel walls to sites of infection and causes fever by affecting areas of the brain that control body temperature. The other form of IL-1, IL-1-beta, acts the same as IL-1-alpha. IL-1-alpha made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. IL-1-alpha is a type of cytokine.,MSH: An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.,NCI: Interleukin-1-Alpha is one of two distinct forms of IL1 encoded by separate genes. IL1(alpha) is the acidic f