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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
1999-2-5
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pubmed:abstractText |
Matrix metalloproteinases (MMP) and their substrates, components of the extracellular matrix, regulate environmental signals for cellular differentiation and tissue function. Changes in the levels of these enzymes may influence cell survival as well as pathology involving ectopic apoptosis. Using the non-obese diabetic (NOD) mouse model for Sjögren's syndrome, we evaluated the synthesis and expression of MMP in the exocrine target tissues of autoimmunity.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0315-162X
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pubmed:author |
pubmed-author:BrayerJJ,
pubmed-author:GarceaRR,
pubmed-author:Humphreys-BeherM GMG,
pubmed-author:KerrMM,
pubmed-author:LowryJ MJM,
pubmed-author:NanniJ MJM,
pubmed-author:NguyenK HKH,
pubmed-author:OxfordG EGE,
pubmed-author:PeckA BAB,
pubmed-author:RobinsonC PCP,
pubmed-author:YamachikaSS,
pubmed-author:da SilveiraAA
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pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2371-80
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9858432-Animals,
pubmed-meshheading:9858432-Cell-Free System,
pubmed-meshheading:9858432-Collagenases,
pubmed-meshheading:9858432-Dipeptides,
pubmed-meshheading:9858432-Disease Models, Animal,
pubmed-meshheading:9858432-Exocrine Glands,
pubmed-meshheading:9858432-Female,
pubmed-meshheading:9858432-Gelatinases,
pubmed-meshheading:9858432-Male,
pubmed-meshheading:9858432-Matrix Metalloproteinase 2,
pubmed-meshheading:9858432-Matrix Metalloproteinase 9,
pubmed-meshheading:9858432-Metalloendopeptidases,
pubmed-meshheading:9858432-Mice,
pubmed-meshheading:9858432-Mice, Congenic,
pubmed-meshheading:9858432-Mice, Inbred BALB C,
pubmed-meshheading:9858432-Mice, Inbred C57BL,
pubmed-meshheading:9858432-Mice, Inbred NOD,
pubmed-meshheading:9858432-Mice, SCID,
pubmed-meshheading:9858432-Parotid Gland,
pubmed-meshheading:9858432-Protease Inhibitors,
pubmed-meshheading:9858432-RNA, Messenger,
pubmed-meshheading:9858432-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:9858432-Saliva,
pubmed-meshheading:9858432-Sjogren's Syndrome,
pubmed-meshheading:9858432-Submandibular Gland,
pubmed-meshheading:9858432-Transcription, Genetic
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pubmed:year |
1998
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pubmed:articleTitle |
Excessive synthesis of matrix metalloproteinases in exocrine tissues of NOD mouse models for Sjögren's syndrome.
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pubmed:affiliation |
Department of Oral Biology, Center for Orphaned Autoimmune Diseases, University of Florida, Gainesville 32610, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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