Linked Life Data

982996

Source:http://linkedlifedata.com/resource/pubmed/id/982996

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1976-12-23
pubmed:abstractText
A model of chronic influenza infection of a strain of human embryo skin-muscle tissue diploid cells (KM WSN) was developed. When the cells were propagated without medium changes, they regularly produced virus in low infectious titres and hemagglutinins in titers of 1 : 2 to 1 : 4. Frequent medium changes caused more intensive infectious virus reproduction with no or very poor hemagglutinin accumulation. Superinfection of KM WSN cultures even with frequent medium changes led to a marked reduction in the amount of infectious virus production with no detectable interferon. The WSN KM virus was found to differ from the initial variant by a number of markers. The observed pattern of virus production suggests a mechanism of persistence in this system in connection with the interfering effect of the defective virus produced by the cells.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0507-4088
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
289-93
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Chronic infection of diploid cells of human embryo musculocutaneous tissue].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract