Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
1998-11-30
|
| pubmed:abstractText |
Two new iridoid glycosides (1 and 2), together with the known compounds barlerin (3) and verbascoside (4), were isolated from Barleria prionitis. The new iridoid glycosides were determined to be 6-O-trans-p-coumaroyl-8-O-acetylshanzhiside methyl ester (1) and its cis isomer (2) by using spectroscopic, especially 2D NMR, data. A 3:1 mixture of 1 and 2 was shown to have potent in vitro activity against respiratory syncytial virus (EC50 2.46 microgram/mL, IC50 42.2 microgram/mL).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0163-3864
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
61
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1295-7
|
| pubmed:dateRevised |
2000-12-18
|
| pubmed:meshHeading |
pubmed-meshheading:9784173-Antiviral Agents,
pubmed-meshheading:9784173-Cytopathogenic Effect, Viral,
pubmed-meshheading:9784173-Glycosides,
pubmed-meshheading:9784173-Magnetic Resonance Spectroscopy,
pubmed-meshheading:9784173-Plants, Medicinal,
pubmed-meshheading:9784173-Respiratory Syncytial Viruses,
pubmed-meshheading:9784173-Thailand
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
New iridoids from the medicinal plant Barleria prionitis with potent activity against respiratory syncytial virus.
|
| pubmed:affiliation |
Shaman Pharmaceuticals, Inc., 213 East Grand Avenue, South San Francisco, California 94080, USA.
|
| pubmed:publicationType |
Journal Article
|