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rdf:type |
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lifeskim:mentions |
umls-concept:C0016030,
umls-concept:C0039194,
umls-concept:C0079189,
umls-concept:C0127082,
umls-concept:C0145947,
umls-concept:C0224522,
umls-concept:C0332158,
umls-concept:C0439851,
umls-concept:C1314939,
umls-concept:C1552596,
umls-concept:C1947931,
umls-concept:C1948023
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pubmed:issue |
10
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pubmed:dateCreated |
1998-11-3
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pubmed:abstractText |
To determine whether direct cell-cell contact with stimulated T lymphocytes (a) differentially modulates the production of interstitial collagenase (matrix metalloproteinase 1 [MMP-1]) and tissue inhibitor of metalloproteinases 1 (TIMP-1) on human synoviocytes and dermal fibroblasts, and (b) induces the production of prostaglandin E2 (PGE2); and to identify the membrane-associated factors on T cell surfaces involved in these mechanisms.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation...,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Surface,
http://linkedlifedata.com/resource/pubmed/chemical/CD69 antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Collagenases,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Lectins, C-Type,
http://linkedlifedata.com/resource/pubmed/chemical/Macrophage-1 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tissue Inhibitor of...,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1748-59
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:9778216-Antibody Formation,
pubmed-meshheading:9778216-Antigens, CD,
pubmed-meshheading:9778216-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:9778216-Antigens, Surface,
pubmed-meshheading:9778216-Cell Communication,
pubmed-meshheading:9778216-Cell Line,
pubmed-meshheading:9778216-Collagenases,
pubmed-meshheading:9778216-Dinoprostone,
pubmed-meshheading:9778216-Fibroblasts,
pubmed-meshheading:9778216-Gene Expression Regulation,
pubmed-meshheading:9778216-Humans,
pubmed-meshheading:9778216-Interleukin-1,
pubmed-meshheading:9778216-Lectins, C-Type,
pubmed-meshheading:9778216-Lymphocyte Activation,
pubmed-meshheading:9778216-Macrophage-1 Antigen,
pubmed-meshheading:9778216-Matrix Metalloproteinase 1,
pubmed-meshheading:9778216-RNA, Messenger,
pubmed-meshheading:9778216-Synovial Membrane,
pubmed-meshheading:9778216-T-Lymphocytes,
pubmed-meshheading:9778216-Tissue Inhibitor of Metalloproteinase-1,
pubmed-meshheading:9778216-Transforming Growth Factor beta
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pubmed:year |
1998
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pubmed:articleTitle |
Imbalance between interstitial collagenase and tissue inhibitor of metalloproteinases 1 in synoviocytes and fibroblasts upon direct contact with stimulated T lymphocytes: involvement of membrane-associated cytokines.
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pubmed:affiliation |
University Hospital of Geneva, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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