|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1998-9-4
|
|
pubmed:abstractText |
Influences of post-natal age (P0-P4) and temperature (22.5 degrees-31.5 degrees C) on the action(s) of opioids on respiratory activities from neonatal rat brainstem-spinal cord preparations were examined in this study. A temperature-dependent mu-opioid receptor effect on respiration was found. In addition, the effect of morphine increased with postnatal age (P0-P4). Hence, age and temperature must be taken into account when performing studies on medullary respiration-related structures using the neonatal rat brainstem-spinal cord preparation.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/3,4-Dichloro-N-methyl-N-(2-(1-pyrrol...,
http://linkedlifedata.com/resource/pubmed/chemical/Analgesics,
http://linkedlifedata.com/resource/pubmed/chemical/Analgesics, Non-Narcotic,
http://linkedlifedata.com/resource/pubmed/chemical/Analgesics, Opioid,
http://linkedlifedata.com/resource/pubmed/chemical/Enkephalin, Ala(2)-MePhe(4)-Gly(5)-,
http://linkedlifedata.com/resource/pubmed/chemical/Enkephalin, D-Penicillamine (2,5)-,
http://linkedlifedata.com/resource/pubmed/chemical/Enkephalins,
http://linkedlifedata.com/resource/pubmed/chemical/Morphine
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0006-8993
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright 1998 All rights reserved.
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
3
|
|
pubmed:volume |
800
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
308-11
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:9685687-3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benz...,
pubmed-meshheading:9685687-Age Factors,
pubmed-meshheading:9685687-Analgesics,
pubmed-meshheading:9685687-Analgesics, Non-Narcotic,
pubmed-meshheading:9685687-Analgesics, Opioid,
pubmed-meshheading:9685687-Animals,
pubmed-meshheading:9685687-Animals, Newborn,
pubmed-meshheading:9685687-Dose-Response Relationship, Drug,
pubmed-meshheading:9685687-Enkephalin, Ala(2)-MePhe(4)-Gly(5)-,
pubmed-meshheading:9685687-Enkephalin, D-Penicillamine (2,5)-,
pubmed-meshheading:9685687-Enkephalins,
pubmed-meshheading:9685687-Medulla Oblongata,
pubmed-meshheading:9685687-Morphine,
pubmed-meshheading:9685687-Rats,
pubmed-meshheading:9685687-Rats, Sprague-Dawley,
pubmed-meshheading:9685687-Respiration,
pubmed-meshheading:9685687-Spinal Cord,
pubmed-meshheading:9685687-Temperature
|
|
pubmed:year |
1998
|
|
pubmed:articleTitle |
Age- and temperature-dependent effects of opioids on medulla oblongata respiratory activity: an in vitro study in newborn rat.
|
|
pubmed:affiliation |
Department of Anesthesiology and Intensive Care, Hokkaido University School of Medicine, Kita-15, Nishi-7, Kita-ku, Sapporo 060, Japan.
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
