rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1998-9-29
|
pubmed:abstractText |
A large number of observations suggest that, during Drosophila development there are close functional interactions between the activity of Notch receptor and that of a signaling molecule encoded by wingless gene. In this essay, I summarize these interactions and discuss the possibility that Wingless acts as a ligand for Notch as part of a switch that is iteratively involved in the assignation of cell fates during development.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Drosophila Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Sorting Signals,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Notch,
http://linkedlifedata.com/resource/pubmed/chemical/Wnt1 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/notch protein, Drosophila,
http://linkedlifedata.com/resource/pubmed/chemical/wg protein, Drosophila
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0214-6282
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
42
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
325-33
|
pubmed:dateRevised |
2010-8-25
|
pubmed:meshHeading |
pubmed-meshheading:9654016-Animals,
pubmed-meshheading:9654016-Body Patterning,
pubmed-meshheading:9654016-Cell Differentiation,
pubmed-meshheading:9654016-Drosophila,
pubmed-meshheading:9654016-Drosophila Proteins,
pubmed-meshheading:9654016-Genes, Switch,
pubmed-meshheading:9654016-Ligands,
pubmed-meshheading:9654016-Membrane Proteins,
pubmed-meshheading:9654016-Protein Sorting Signals,
pubmed-meshheading:9654016-Proto-Oncogene Proteins,
pubmed-meshheading:9654016-Receptors, Notch,
pubmed-meshheading:9654016-Wnt1 Protein
|
pubmed:year |
1998
|
pubmed:articleTitle |
Interactions between Wingless and Notch during the assignment of cell fates in Drosophila.
|
pubmed:affiliation |
Department of Zoology, University of Cambridge, United Kingdom. ama11@cus.cam.ac.uk
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|