Linked Life Data

9651967

Source:http://linkedlifedata.com/resource/pubmed/id/9651967

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1998-9-22
pubmed:abstractText
Whole-embryo culture was used as the model system to study the effects of pulsed ultrasound on embryonic development. Rat embryos (9.5 days old) were exposed to a wide range of ultrasound levels at ultrasound frequencies between 1-4 MHz for 30 min in vitro. After 48 h in culture, absolute control, sham and treatment embryos were assessed for viability, morphology, growth and development. At an ambient temperature of 37 degrees C, no significant effects were observed for spatial peak temporal average intensities below 4 W/cm2 or peak negative pressures below 1.9 MPa. At higher acoustic levels, there was a significant increase in the number of nonviable embryos and the number of morphological abnormalities in viable embryos increased. Abnormal cephalocaudal flexion and abnormal head development were the most common gross morphological abnormalities. Both thermal and nonthermal bioeffect mechanisms are involved.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0301-5629
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
575-85
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Effects of pulsed ultrasound on embryonic development: an in vitro study.
pubmed:affiliation
Department of Medical Physics and Bioengineering, St. George's Healthcare NHS Trust, London, UK. kramnarine@ed.ac.uk
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't