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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1998-9-25
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pubmed:abstractText |
Glutaraldehyde is considered a promoter of calcification by the action of toxic aldehyde group residuals from cross-linking. Post-fixation treatment with homocysteic acid (HA), besides bonding aldehyde groups and neutralizing toxicity, should enhance biocompatibility due to the strongly electronegative sulfonic group. The aim of this investigation was to evaluate HA efficacy on tissue preservation and dystrophic calcification mitigation in glutaraldehyde cross-linked bovine pericardium (BP) using a subcutaneous rat model.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0966-8519
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pubmed:author |
pubmed-author:De GiorgiGG,
pubmed-author:GattiA MAM,
pubmed-author:GiarettoSS,
pubmed-author:MartignagoFF,
pubmed-author:MolinG MGM,
pubmed-author:PasquinoEE,
pubmed-author:PettenazzoEE,
pubmed-author:RinaldiSS,
pubmed-author:TalentiEE,
pubmed-author:ThieneGG,
pubmed-author:ValentaAA
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
283-91
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9651841-Animals,
pubmed-meshheading:9651841-Biocompatible Materials,
pubmed-meshheading:9651841-Bioprosthesis,
pubmed-meshheading:9651841-Calcinosis,
pubmed-meshheading:9651841-Cattle,
pubmed-meshheading:9651841-Electron Probe Microanalysis,
pubmed-meshheading:9651841-Glutaral,
pubmed-meshheading:9651841-Heart Valve Prosthesis,
pubmed-meshheading:9651841-Homocysteine,
pubmed-meshheading:9651841-Male,
pubmed-meshheading:9651841-Microscopy, Electron,
pubmed-meshheading:9651841-Microscopy, Electron, Scanning,
pubmed-meshheading:9651841-Pericardium,
pubmed-meshheading:9651841-Rats,
pubmed-meshheading:9651841-Rats, Sprague-Dawley,
pubmed-meshheading:9651841-Time Factors,
pubmed-meshheading:9651841-Tissue Preservation,
pubmed-meshheading:9651841-X-Ray Diffraction
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pubmed:year |
1998
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pubmed:articleTitle |
Detoxified glutaraldehyde cross-linked pericardium: tissue preservation and mineralization mitigation in a subcutaneous rat model.
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pubmed:affiliation |
University of Padua and Modena, Sorin Biomedica-Cardio, Saluggia, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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