Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-4-21
pubmed:abstractText
The development of methods employing the introduction of new genetic material for therapeutic applications in the cardiovascular system is dependent not only on the evolution of molecular vectors, but also 'mechanical vectors' encompassing a variety of mechanisms and approaches for the delivery of vectors or vector-modified cells to anatomical regions of interest. A significant challenge lies in the evolution of mechanical devices capable of highly efficient, localized and homogeneous delivery. Each of these three characteristics, though very desirable, remains generally elusive for several kinetic and physical reasons. Recently developed devices which render possible minimally-invasive peri- or epivascular delivery may provide advances in these aspects of delivery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1084-2764
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
215-23
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Methods of local gene delivery to vascular tissues.
pubmed:affiliation
Krannert Institute of Cardiology, Indianapolis, IN 46202, USA. march@kimail.dmed.iupui.edu
pubmed:publicationType
Journal Article, Comparative Study, Review