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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1998-4-9
|
| pubmed:abstractText |
Phosphodiesterases (PDE) are key enzymes in the regulation of the smooth muscle tone. Experimental studies showed PDE III and V-isoenzymes to play an important role in the smooth muscle tone regulation of corpus cavernosum. Recently, a specific PDE III-inhibitor (milrinone) and a PDE V-inhibitor (sildenafil) were introduced in clinical studies. An experimental study was done to examine a potential role of PDE-inhibitors in the treatment of erectile dysfunction.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0022-5347
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
159
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1390-3
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9507890-Animals,
pubmed-meshheading:9507890-Dose-Response Relationship, Drug,
pubmed-meshheading:9507890-Erectile Dysfunction,
pubmed-meshheading:9507890-Humans,
pubmed-meshheading:9507890-Male,
pubmed-meshheading:9507890-Penis,
pubmed-meshheading:9507890-Phosphodiesterase Inhibitors,
pubmed-meshheading:9507890-Rabbits
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
The effect of the specific phosphodiesterase (PDE) inhibitors on human and rabbit cavernous tissue in vitro and in vivo.
|
| pubmed:affiliation |
Dept. of Urology, Medizinische Hochschule Hannover, Germany.
|
| pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|