rdf:type |
|
lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1998-2-26
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pubmed:abstractText |
Ischemic brain injury secondary to an arterial occlusion is characterized by acute local inflammation. Blood polymorphonuclear leukocytes (PMNL), primarily neutrophils, adhere to endothelial cells and rapidly invade the injured brain after the arterial occlusion. This neutrophilic invasion might correlate with the production of certain chemoattractants by blood mononuclear cells (MNC). We evaluated mRNA expression of the CXC chemokine interleukin (IL)-8, and the CC chemokines monocyte chemoattractant protein-1, macrophage inflammatory protein (MIP)-1alpha, and MIP-1beta in blood MNC from patients with ischemic stroke.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
pubmed:issn |
0039-2499
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
29
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
462-6
|
pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9472890-Aged,
pubmed-meshheading:9472890-Aged, 80 and over,
pubmed-meshheading:9472890-Brain Ischemia,
pubmed-meshheading:9472890-Chemokine CCL2,
pubmed-meshheading:9472890-Chemokine CCL3,
pubmed-meshheading:9472890-Chemokine CCL4,
pubmed-meshheading:9472890-Female,
pubmed-meshheading:9472890-Humans,
pubmed-meshheading:9472890-Interleukin-8,
pubmed-meshheading:9472890-Leukocytes, Mononuclear,
pubmed-meshheading:9472890-Macrophage Inflammatory Proteins,
pubmed-meshheading:9472890-Male,
pubmed-meshheading:9472890-Middle Aged,
pubmed-meshheading:9472890-RNA, Messenger,
pubmed-meshheading:9472890-Reference Values,
pubmed-meshheading:9472890-Regression Analysis,
pubmed-meshheading:9472890-Transcription, Genetic
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pubmed:year |
1998
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pubmed:articleTitle |
Ischemic stroke is associated with a systemic increase of blood mononuclear cells expressing interleukin-8 mRNA.
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pubmed:affiliation |
Division of Neurology, Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden. Nikolakis@hotmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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