Linked Life Data

9459382

Source:http://linkedlifedata.com/resource/pubmed/id/9459382

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1998-2-24
pubmed:abstractText
To investigate whether resistant starch (RS) affects putative risk factors for colon cancer, 24 healthy men consumed a daily RS supplement for 4 wk in addition to their habitual diet in a single-blind, randomized, balanced multiple crossover trial. During the first week, all subjects consumed the control supplement containing glucose. Subsequently, each subject consumed, in random order, a supplement with RS2 (uncooked high-amylose cornstarch), RS3 (extruded and retrograded high-amylose cornstarch), and glucose, each for 1 wk. The RS2 and RS3 supplements provided 32 g RS/d. Lithium was added to the supplements to measure compliance. Feces, 24-h urine, and breath samples, as well as a 24-h food-consumption recall were obtained weekly from each subject. Compliance as measured by urinary lithium recovery was satisfactory. The mean composition of the background diet did not differ between the various supplementation periods. Breath-hydrogen excretion, stool weight, and fecal starch excretion were significantly higher during RS than during glucose supplementation, but did not differ during RS2 and RS3 supplementation. There were no significant differences in fecal dry weight, pH, or short-chain fatty acid concentrations, nor in the pH, bile acid concentrations, cytotoxicity, or osmolality of fecal water. It is concluded that in healthy men, supplementing the habitual diet for 1 wk with 32 g RS2 or RS3/d compared with glucose had no effect on putative risk factors for colon cancer, except for increasing stool weight and colonic fermentative activity. There were no significant differences between the effects of RS2 and RS3 on the indexes studied.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0002-9165
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
322-31
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Limited effect of consumption of uncooked (RS2) or retrograded (RS3) resistant starch on putative risk factors for colon cancer in healthy men.
pubmed:affiliation
Department of Human Nutrition, Wageningen Agricultural University, The Netherlands. marie-louise.heijnen@rivm.nl
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't